• Alkaloids, anthocyanins, caffeoylquinic acid, common Hydrangea, French hydrangea, glucosylcyanidin anthocyanins, glucosyldelphinidin, guilder rose, H. hortensia, hydragenol, Hydrangea arborescens, Hydrangea arborescens L., Hydrangea ashei Harbison, Hydrangea cinerea, hydrangea extract, Hydrangea macrophylla, Hydrangea macrophylla Thunb., Hydrangea paniculata Sieb., Hydrangea quercifolia Bart, Hydrangea radiata Walt., Hydrangea vulgaris, Hydrangea xanthoneura, Hydrangeaceae (family), Hydrangeae Dulcis Folium, hydrangeaic acid, hydrangenol, hydrangeol, hydrangin, mountain hydrangea, oakleaf hydrangea, panicled hydrangea, seven barks, silverleaf hydrangea, small ashy hydrangea, smooth hydrangea, wild hydrangea.

• Hydrangea is an ornamental plant native to North and South America and eastern and southern Asia. It has been used for the treatment of urinary tract disorders in traditional Chinese medicine and by the Cherokee tribe of North America.
• Preliminary study has investigated hydrangea for its potential antifungal, antimalarial, and blood sugar-lowering properties. When applied to the skin, hydrangea may prevent male pattern baldness.
• There is currently not enough human evidence available to support the use of hydrangea for any indication.

• Allergies, antifungal, anti-malarial, bladder disorders, bladder inflammation, cathartic, diuretic, enlarged prostate, hyperglycemia (high blood sugar levels), inflammation (urethra), kidney stones, male baldness, prostate inflammation, salivation stimulant, urinary stones, urinary tract disorders.

Adults (18 years and older)

• Hydrangea has been consumed as a powdered herb, liquid extract, syrup, tincture, and tea. Doses have included 2 to 4 grams dried hydrangea rhizome and root three times per day; 2 to 4 milliliters hydrangea liquid extract three times per day; 1 teaspoon hydrangea syrup three times per day; 2 to 10 milliliters hydrangea tincture three times per day; and 2 to 4 grams dried hydrangea rhizome and root steeped in 150 milliliters boiling water for 5 to 10 minutes three times per day.

Children (under 18 years old)

• There is no proven safe or effective dose for hydrangea, and use in children is not recommended.

Allergies

• Avoid with known allergy or hypersensitivity to hydrangea. Symptoms of allergic reaction include rash, eczema, and inflammation.

Side Effects and Warnings

• Hydrangea may lower blood sugar levels. Caution is advised in patients with diabetes or low blood sugar or in those taking drugs, herbs, or supplements that affect blood sugar. Blood glucose levels may need to be monitored by a qualified healthcare professional and medication adjustments may be necessary.
• Hydrangea may cause dizziness and chest tightness. Use with caution in people with gastrointestinal disorders.

Pregnancy and Breastfeeding

• Hydrangea is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence.

Interactions with Drugs

• Hydrangea may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. Patients taking drugs for diabetes by mouth or injection should be monitored closely by a qualified healthcare professional. Medication adjustments may be necessary.
• Hydrangea may add to the effects of antifungal, anti-malarial, antihistamine, and cholesterol-lowering drugs, and drugs taken to prevent hair loss.

Interactions with Herbs and Dietary Supplements

• Hydrangea may lower blood sugar levels. Caution is advised when using herbs or supplements that may also lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.
• Hydrangea may add to the effects of herbs and supplements with antifungal, antihistamine, anti-malarial, and cholesterol-lowering effects, and herbs and supplements taken to prevent hair loss.

• This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).

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